Asian Journal of Pharmaceutical Analysis

Somsubhra Ghosh ¹, V. Laxmi Prasanna ¹, B. Sowjanya ¹, P. Srivani ¹, M. Alagaraja ², David Banji ¹

Affiliations
1 Nalanda College of Pharmacy, Nalgonda, Andhra Pradesh – 508001, IN
2 Nalanda College of Pharmacy, Nalgonda, Andhra Pradesh – 508001, HK

Abstract

Spectroscopy is the chief experimental technique of atomic and molecular physics and involves determining the energy states of atoms or molecules by looking at the light absorbed or emitted when they change states. Measuring the frequency of light absorbed or emitted which is determined by the energy difference between the two states, can provide a sensitive probe of interactions which perturb those energy states. Among those in this review we revealed that the principle, instrumentation and applications of inductively coupled plasma optical emission spectroscopy. In this sample is usually transported into the instrument as a stream of liquid sample. Inside the instrument, the liquid is converted into an aerosol through a process known as nebulisation. The sample aerosol is then transported to the plasma where it is desolvated, vaporized, atomized, and excited and/or ionized by the plasma. The excited atoms and ions emit their characteristic radiation which is collected by a device that sorts the radiation by wavelength. The radiation is detected and turned into electronic signals that are converted into concentration information for the analyst.

Keywords

Spectroscopy , Nebulisation, Desolvation, Plasma

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Somsubhra Ghosh ¹, Arnab Jana ¹, Beduin Mahanti ¹

Affiliations
1 Department of Pharmaceutical Analysis, Bharat Technology, Uluberia, Howrah, W. B-711316, IN

Abstract

For centuries, our sense of smell has been used as a diagnostic tool in the practice of medicine, be it for recognising gas gangrene on the battle field or diabetic ketoacidosis in the emergency room. In recent decades, many scent detection studies have been performed with human, animal and electronic noses. The ability of humans to diagnose disease by smelling has only rarely been the subject of quantitative studies. Scent detection by animals, on the other hand, has been addressed in several diagnostic studies, which all suggest similar or even superior accuracy compared with standard diagnostic methods. Examples include, amongst many others, the use of dogs for the detection of lung cancer in breath samples, or rats for Mycobacterium tuberculosis detection in sputum. Studies using different types of electronic noses in conditions such as pulmonary disease and cancer have also shown promising results with high overall sensitivity and specificity. However, results of different types of noses are not easily general sable and independent confirmation studies are generally lacking, which should be a focus for future research. Scent detection by animals and electronic noses holds promise for the future and should receive higher priority in terms of research effort and funding.

Keywords

Cancer, Trained Dog, Blood Sugar, Medical Detection, Sence.

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Goli Venkateshwarlu ¹, Manoranjan Sabath ¹, G. Venugopal ¹, M. Sravanprasad ², Somsubhra Ghosh ³, Sama Bharathbhushanreddy ¹

Affiliations
1 Venkateshwara Institute of Pharmaceutical Sciences, Nalgonda, IN
2 Sriindu Institute of Pharmaceutical Sciences, Sheriguda, R.R Dist., IN
3 Nalanda College of Pharmacy, Nalgonda, IN

Abstract

The determination of surface tension of three selected marked juice formulations were carried out using Traube's Stalagnometer technique by drop number method which in turn aid in further identification, structural elucidation as well as determining chemical constituents. The formulation I (Lemon Juice), formulation II (Tamarind Juice) and formulation III (Orange Juice) were selected for the studies and were also evaluated to their same quantity mixture ration with distilled water combination for estimation of different composition. The main aim and rationale of study was to evaluate the surface tension of selected formulations with distilled water. The 10% formulation of mixture (I:II:III::1:1:1) with distilled water showed maximum surface tension (72 dyne/cm) and 10% formulation mixture with distilled water showed minimum surface tension ( 65 sdyne/cm) amongst other compositions. The results revealed that all the present composition values were less than standard. The 60% (74 sdyne/cm), 70% (67.8 dyne/cm), 80% (68.07 dyne/cm), 90% (71.8s dyne/cm) formulation mixture with distilled water showed approximately same surface tension value. In individual surface tension study, it was noted that formulation III i.e. tamarinds juice (60 dyne/cm) showed highest value and formulation I i.e. Orange Juice (61 dyne/cm) showed lowest value comparison between three formulations under laboratory conditions.

Keywords

Surface Tension, Juice Formulation, Drop Number Method, Traube's Stalagnometer.

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